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49ers Vs CardinalsSan Francisco 49ers Vs Arizona Cardinals

The full NFL schedule doesn't come out for another week, but the Cardinals now know the details of their game in Mexico City this season – and that it will be a nationally televised primetime game.

The NFL announced Wednesday morning the Cardinals will play the San Francisco 49ers at Estadio Azteca on "Monday Night Football" on Nov. 21. Kickoff will be at 7:15 p.m. in Mexico City (6:15 p.m. Arizona time.)

The Cardinals also played the 49ers when they became the first team to win a regular-season game outside the United States, 31-14, in a game at Estadio Azteca in 2005. The NFL has not held a game in Mexico City for two years because of Covid.
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